ІRSTІ 61.39.81, 64.29.23                                                                       №4 (2019г.)

Dzhuraev H. F. Gafurov, K. H., Muhammad, B. T., Sh. Mirzaev U.  

Extraction of GA from licorice roots was carried out by SK-CO2 using ethanol as a solvent. Experiments and simulations were designated through RSM. The licorice root extract was analyzed by chromatography and AAS. The RSM design was used to optimize the variables of the SLE and the output of the HA. The maximum GA yield is observed under conditions of 10 MPa, 90.8 and 48.2°C, 92 min and a flow of 1.70 and 1.50 ml/min of CO2 using RSM, respectively. According to RSM R2 and the modified R2 model is 96.1% and 93.2%, accordingly. The accuracy of the GA yield model is confirmed by triplet experiments giving an average extraction yield of 52.2±1.2%, respectively, for RSM.
Keywords: SC fluid extraction, RSM, licorice root, modeling.